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Catch 2: Catch 3: Skin-homing CCR8+ T cells are critical for spontaneous experimental autoimmune uveoretinitis and photoreceptor death in mice.
Previous studies have demonstrated that tissue-derived chemokines can affect the development of autoimmune diseases. To determine the role of chemokine receptors in the development of experimental autoimmune uveoretinitis (EAU), we studied the kinetics of recruitment of different chemokine receptor-positive T cell subsets into the draining lymph nodes of mice with spontaneous EAU. We also examined the effects of blocking chemokine receptors on the initiation and progression of EAU. The development of EAU was delayed in mice in which the CCR5 chemokine receptor was blocked. In contrast, both CCR8- and CCR6-expressing T cells were required to mediate spontaneous EAU. The CCR8-expressing T cells were crucial for disease initiation in that they were required for the induction of interphotoreceptor retinoid-binding protein (IRBP) epitope-specific T cells and the destruction of photoreceptors. However, the CCR6-expressing cells were important for disease progression, because the blockade of this receptor did not affect the initiation but did retard disease progression. Our data demonstrate a differential role for chemokine receptors in the initiation and progression of this disease model.Q:
Exit from / trigger javascript function
I want to create a function that can close current page and refresh another page when the page is closed.
I have read that I can use exit() method from other scripts but I don't know how to trigger this.
Can someone help?
A:
There is no way to trigger exiting a page. The exiting is done when the page is loaded.
But you can redirect to a new page, and you also can use javascript to clear the current page.
index.php?page=foo
On 'foo' page var qq = window.location.search; window.location.
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